Twitch

Caitlyn out-ranges Twitch by 100 units, 650 against 550, and her Yordle Snap Trap W plus Piltover Peacemaker Q line control the brush angle Ambush Q relies on. Headshot passive procs out-trade Deadly Venom ramping, 90 Caliber Net E slows him while the recoil carries her away.

Draven out-trades Twitch in the level 1-6 window before Deadly Venom passive can stack 6 — Spinning Axe Q auto-empowers chunk his low base HP. League of Draven passive bonus gold snowballs early items, Blood Rush W chases Ambush Q stealth angles.

Elise's Cocoon E in human form is a skillshot stun that lands the instant Twitch's Ambush Q stealth drops. Neurotoxin Q applies %-current-HP burst, Volatile Spiderling W chases through fog, Rappel E spider-form descend dodges Spray and Pray R chains.

Lee Sin's Sonic Wave Q damages Twitch out of Ambush Q camouflage on contact, and the Resonating Strike follow-up dashes to him for missing-health damage. Tempest / Cripple E reveals every enemy it hits, Safeguard / Iron Will W omnivamp sustains the duel.

Lucian out-trades Twitch in the level 1-6 window before Deadly Venom passive can stack 6 — Lightslinger passive double-shot plus Relentless Pursuit E gap-close lets him burst Twitch before Ambush Q stealth comes online.

Twisted Advance (W) is point-and-click root that reveals Twitch through Ambush (Q) invisibility before he can pick angles. Spray and Pray (R) requires standing still — Sap Magic (P) heal out-sustains the trade and Nature's Grasp (R) cuts his escape paths.

Twitch needs Ambush camouflage to set up Spray and Pray autos from safety; he has no dash to answer a pull, and Apotheosis drags him out of position into Nilah's frontline.

Samira's Wild Rush E dash plus Inferno Trigger R delete Twitch inside his Spray and Pray R window before the piercing autos can finish. Daredevil Impulse passive ramps her style rank on every Flair Q proc, Blade Whirl W destroys the Venom Cask W missile before it lands.

Twitch has no dash whatsoever and Ambush Q only grants Camouflage, which enemies see through at close range. Talon's Shadow Assault R-invisibility approaches faster than his Ambush windup, Rake W locks him in melee with slow plus return daggers.

Vi's Vault Breaker Q charge tags Twitch through fog, knocks him back and breaks Ambush Q stealth on contact, and Cease and Desist R single-target lock chains the second knock-up. Denting Blows W shreds Armor on every third hit, Relentless Force E blasts through him.

Warwick's Infinite Duress R targets Twitch from any range as a leap-suppress that cannot be cleansed by Mercury's Treads. Blood Hunt W speeds him toward Twitch the moment Twitch drops below half health, Jaws of the Beast Q heals through Deadly Venom passive ticks.

Xin Zhao's Audacious Charge E dash damages everything in the landing area, breaking Ambush Q camouflage before the ambush resolves. Three Talon Strike Q third-hit knock-up locks Twitch in melee, Wind Becomes Lightning W cone slows the kite.

Twitch's Ambush Q stealth opener requires closing to roughly 550 attack range to land Deadly Venom stacks. Yunara's Arc of Judgment W slows at 1150 and Cultivation of Spirit Q on-hit plus attack speed wins the trade before Contaminate E procs.

Twitch has no dash and no instant CC against gap-closers. Zed's Death Mark R lands on his back-line spot before Ambush Q can refresh stealth, Living Shadow W swap closes the gap, Razor Shuriken Q chip pre-bursts him.