Renata Glasc

Kayle's Divine Judgment R makes the ally invulnerable, cancelling Bailout's death-delay since they cannot be damaged to trigger the save — the second-life passive never procs.

Lulu's Whimsy W polymorphs Renata's ADC mid-Bailout buff, cancelling the second life before it triggers — the W save target loses auto-attacks during the polymorph so the Takedown timer cannot lock.

Milio's Breath of Life R cleanses the Handshake Q-recast stun and applies Tenacity, removing Renata's only hard crowd control chain. Warm Hugs E speed-shield pulls the ADC out of Hostile Takeover R cone before the berserk lands.

Morgana's Black Shield E blocks Handshake's initial root outright — no recast becomes available because the Q never connects. Dark Binding root locks Renata during the Hostile Takeover R cast windup, and Soul Shackles tether ult chains a stun during the Handshake recast attempt.

Renata's Bailout (W) saves the ADC reactively but does nothing about Senna positioning at 1250 range. Handshake (Q) is a 900-range skill-shot that misses behind soul positioning, and Hostile Takeover (R) is a cone Senna can stand outside of while she stacks.

Bailout (W) save window is short-range and cannot reach a Shaco-flanked ADC. Deceive (Q) crit plus Two-Shiv Poison (E) execute kills the carry before Hostile Takeover (R) berserks anyone, and the W fear chain breaks her Handshake (Q) hook channel.

Xerath's Arcanopulse Q out-ranges Loyalty Program E shield, chipping HP for free past 1200 units. Handshake Q is too slow vs instant Shocking Orb stun skillshot, and Rite of the Arcane R channel executes Renata's ADC from across the map after the lane phase.