Vex

Annie Pyromania passive every fourth spell stuns through Summon Tibbers (R) point-and-click target, bypassing Doom 'n Gloom passive because it is not a dash, so the engage lands and Personal Space (W) never peels. Disintegrate (Q) plus Incinerate (W) bursts her low HP fast.

Lissandra Frozen Tomb (R) lands point-blank without a dash, bypassing Doom 'n Gloom passive trigger. Ring of Frost (W) root locks Vex mid Mistral Bolt (Q) cast and Glacial Path (E) does not trigger her passive because the claw projects before the dash, denying her self-peel fear.

Vex's Doom 'n Gloom punishes dashes but Nocturne's R is a leap with no in-air mobility window for her passive to read, so the Personal Space fear procs only after he has already landed and committed E.

Twisted Fate Pick a Card (W) gold-card stun is a point-and-click lock that bypasses Doom 'n Gloom passive because it is not a dash, so the engage lands cleanly and her Personal Space (W) never gets the chance to peel.

Vel'Koz Plasma Fission (Q) bends around minions and out-ranges Vex Mistral Bolt (Q) 1200 and Looming Darkness (E) 800, so she has no dash to close the gap. Tectonic Disruption (E) knock-up cancels her Mistral Bolt (Q) cast and Life Form Disintegration Ray (R) burns her low HP.

Xerath Arcanopulse (Q) 1450 range out-ranges Vex Mistral Bolt (Q) 1200 and Looming Darkness (E) 800, so she has no dash to close the gap and eats poke every wave. Rite of the Arcane (R) snipes from off-screen and Shocking Orb (E) stuns her if she steps up to commit.